Neuro-Ocular Session Report
CGT · Session 04827 · 19 May 2026
Bethesda Clinical Validation Hub
Clinician: M. Duplessie, MD
Device: Varjo XR-4 · Tracker 200 Hz
Protocol: CGT-15B-Scenario v7.0
Patient
M. R.
Age · Sex
16 · M
Scenario
ATC Tower
Session Type
Post-Injury · Day 8
Duration
06:42 / 06:30 ref
Data Quality
Good · 94.3%
Composite Result

A measurable signal across the vestibulo-ocular axis, consistent with day-8 post-concussive presentation.

The composite Neurological Readiness Index aggregates the fifteen biomarkers, weighted by validated effect-size against an age- and sex-matched normative cohort. This patient's score sits 2.1 standard deviations below the cohort mean on a downward trajectory from the symptom-onset baseline three days prior, with a measurable recovery vector observed since session 04812 (day 5). Primary signal in the vestibular and ocular subtype channels; secondary signal in cognitive-fatigue.

Neurological Readiness Index
68 / 100
⏵ Borderline · Monitor
0
40
60 · cohort μ-1σ
85 · cohort μ
100

Z-score -2.1 vs age-matched athletic cohort.

Trend over last 3 sessions: +4.2 points (recovering).

Subtype signal: vestibular, ocular.

The Fifteen Biomarkers

Per-biomarker measurement, compared against published normative ranges.

Acquisition window 06:42

Engbert–Mergenthaler λ·MAD detection

Per-trial validity flags applied

01
Fixation Stability
0.21deg²
Normal < 0.30 deg²
Within Range
02
Pupillary Light Reflex / RAPD
0.08log
RAPD threshold < 0.30
Within Range
03
Saccadic Latency · Gap
218ms
Normal 150 – 200 ms
Elevated
04
Peak Saccadic Velocity
578%
Main seq · cohort match
Within Range
05
Saccadic Accuracy / Gain
0.82
Normal 0.85 – 0.95
Hypometric
06
Vertical Saccades
0.91
Up/down ratio · symmetric
Within Range
07
Antisaccade Error Rate
28%
Cohort 10 – 25 %
Mildly Elevated
08
Reading Saccades · Fixation
238ms
Normal 200 – 250 ms
Within Range
09
Smooth Pursuit Gain
0.74
Normal 0.85 – 0.95
Reduced
10
Vergence · Near-Point
9.5cm
Normal 4 – 6 cm
Receded
11
Vestibulo-Ocular Reflex
0.78
Normal 0.94 – 1.00
Reduced VOR Gain
12
Optokinetic Nystagmus
0.81
Normal > 0.85 · asym 8 %
Asymmetry Detected
13
Inter-Saccadic Interval
242ms
Normal 200 – 350 ms
Within Range
14
Contrast Sensitivity
1.95log
Pelli-Robson · cohort match
Within Range
15
Choice Reaction Time
312ms
Normal 200 – 280 ms
Slowed
Pittsburgh-Five Subtype Mapping

Where the signal lives — biomarkers aggregated to the validated clinical subtypes.

Vestibular
7.2 / 10
VOR · OKN · Smooth Pursuit · Vergence
Ocular
6.4 / 10
Saccadic Latency · Gain · Vergence · Antisaccade
Cognitive · Fatigue
4.1 / 10
Antisaccade · Reaction Time · ISI
Post-Traumatic Migraine
1.3 / 10
PLR · Contrast Sensitivity · Fixation
Anxiety · Mood
0.9 / 10
PLR autonomic · Antisaccade · ISI

Subtype-Weighted Clinical Picture

The biomarker signal concentrates in the vestibular and ocular subtype channels, with a secondary cognitive-fatigue signal that is modest and likely arousal-mediated. The post-traumatic-migraine and anxiety-mood channels are quiet.

The pattern is consistent with a post-concussive presentation centered on the vestibulo-ocular axis — vergence insufficiency, reduced VOR gain, reduced smooth-pursuit gain, and mild OKN asymmetry — without a measurable migrainous or affective component. Reading and contrast-sensitivity channels are unaffected, suggesting the optic-pathway and cortical visual machinery are intact.

  • Vestibular and ocular subtype signal is the clinical fingerprint of this presentation.
  • Two of the three "outside-range" biomarkers (VOR, vergence) map to the vestibulo-ocular pathway; smooth pursuit overlaps both.
  • The cognitive-fatigue signal is consistent with day-8 post-injury arousal and attention compromise rather than primary cognitive injury.
  • Recommended trajectory: targeted vestibular rehabilitation; convergence-insufficiency exercises; serial monitoring at 72-hour intervals.
Biomarker Detail

Smooth Pursuit · Time-series gaze trace vs target.

Sample 200 Hz binocular · 30-s window

Engbert–Mergenthaler segmentation

Catch-up saccade events flagged

Horizontal Pursuit Trace
Target ± 10° at 10 °/s · triangular wave · 5 cycles
REDUCED GAIN
Gain · Left
0.76
norm 0.85 – 0.95
Gain · Right
0.73
norm 0.85 – 0.95
Catch-up Sacc/sec
1.8
norm < 0.6
Vertical Pursuit Trace
Target ± 6° at 8 °/s · triangular wave · 4 cycles
WITHIN RANGE
Gain · Up
0.89
norm 0.85 – 0.95
Gain · Down
0.84
norm 0.85 – 0.95
Catch-up Sacc/sec
0.4
norm < 0.6
Longitudinal Trajectory

Composite Index across sessions — pre-injury baseline through day 8.

7 sessions over 38 days

Acute injury · 11 May 2026

Trend Δ = +4.2 over last 72 h

Clinician Interpretation

Narrative synthesis and clinical recommendation.

Summary of Findings

Sixteen-year-old male athlete, day 8 following a sport-related concussion sustained 11 May 2026 during a soccer match. Pre-injury baseline session 04621 (28 April) demonstrated all fifteen biomarkers within range and a composite index of 92. Acute post-injury session 04812 (day 5) demonstrated a composite of 61 with measurable signal across vestibular, ocular, and cognitive-fatigue channels.

Today's session (day 8) shows a composite of 68, a four-point improvement over day 5, with the migraine and anxiety-mood channels essentially quiet. The persistent signal in VOR gain (0.78), near-point of convergence (9.5 cm), and smooth pursuit gain (0.74 left / 0.73 right) is consistent with vestibulo-ocular subtype, the most prevalent post-concussive clinical phenotype in adolescent athletes per the Pittsburgh-five framework.

Reading-saccade fixation duration, contrast sensitivity, fixation stability, and pupillary light reflex with RAPD are all within range — the optic-pathway and primary visual cortex are not implicated.

This is a measurable recovery trajectory. The patient is not yet at baseline, but the direction of travel is favorable.

Return-to-X Recommendation
Maintain modified-activity status. Re-test in 72 hours.
Return to Play ⏸ Hold
Return to School ⚠ Modified
Return to Reading ✓ Cleared
Screen-Time Limits ⚠ ≤ 90 min
Driving ⚠ Daylight Only
Follow-up: Re-test 22 May 2026 (day 11). If VOR gain ≥ 0.90 and near-point ≤ 7 cm at re-test, advance to graduated return-to-play protocol stage 3. Targeted vestibular rehabilitation referral submitted.